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Rotem Industries intem ct rotem based anticoagulation management
Intem Ct Rotem Based Anticoagulation Management, supplied by Rotem Industries, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Clinical Proteomics:

Article Title: Viscoelastic testing in oncology patients (including for the diagnosis of fibrinolysis): Review of existing evidence, technology comparison, and clinical utility.
Article Snippet: .. For example, ROTEM was able to associate multiorgan failure with fibrinolytic shutdown.Scarlatescu et al68 demonstrated that plasma indicators of fibrinolysis and standard coagulation tests were inadequate to assess risk of bleeding and thrombosis with malignancy and sepsis.68 Another study by Hincker et al8 of patients with malignancies undergoing noncardiac surgery demonstrated that preoperative EXTEM and INTEM (individual ROTEM assays) showed decreased CFT, increased α-angle, and increased MCF in patients with thromboembolic complications. ..

Coagulation:

Article Title: Viscoelastic testing in oncology patients (including for the diagnosis of fibrinolysis): Review of existing evidence, technology comparison, and clinical utility.
Article Snippet: .. For example, ROTEM was able to associate multiorgan failure with fibrinolytic shutdown.Scarlatescu et al68 demonstrated that plasma indicators of fibrinolysis and standard coagulation tests were inadequate to assess risk of bleeding and thrombosis with malignancy and sepsis.68 Another study by Hincker et al8 of patients with malignancies undergoing noncardiac surgery demonstrated that preoperative EXTEM and INTEM (individual ROTEM assays) showed decreased CFT, increased α-angle, and increased MCF in patients with thromboembolic complications. ..

Article Title: Effect of the colloids gelatin and HES 130/0.4 on blood coagulation in cardiac surgery patients: a randomized controlled trial.
Article Snippet: Objective: The choice of the prime solution for cardiopulmonary bypass can play an important role in limiting the effect on blood coagulation, but it is still unclear what the effect of colloids on blood coagulation is.. The aim of this study was to investigate the effect of synthetic colloids on blood loss and blood coagulation in patients after on-pump coronary artery bypass graft (CABG) procedures.. Methods: Sixty elective, on-pump CABG patients were randomly assigned to receive the prime solutions lactated Ringer’s solution combined with hydroxyethyl starch 130/0.4 (HES, 6% Volulyte, Fresenius Kabi Nederland BV, Zeist, the Netherlands) (HES group) or gelatin (Gelofusin®, B Braun Melsung AG, Melsungen, Germany) (Gelo group).

Article Title: Validation of viscoelastic coagulation tests during cardiopulmonary bypass.
Article Snippet: .. Across all measurements, the correlation between inTEM (ROTEM) and heparinase TEG was good with BMI, body mass index; CBP, cardiopulmonary bypass; INR, international normalized ratio; APTT, activated partial thromboplastin time; ABG, arterial blood gas; Hb, hemoglobin; Hct, hematocrit; ACT, activated clotting time. ..

other:

Article Title: Robotic Lung Volume Reduction Surgery With Extracorporeal Membrane Oxygenation.
Article Snippet: Lobectomy for consolidation of failed endoscopic lung volume reduction for emphysema has been reported in selected patients with favorable results but with considerable morbidity.. The challenging issues in such patients are frailty caused by severe emphysema itself, poor tolerance to single-lung ventilation, target lobe hyperinflation, and inability to use gas inflation for the minimally invasive resection.. Careful planning, including use of a robotic platform and extracorporeal membrane oxygenation support, can circumvent such difficulties and ensure a safe, minimally invasive resection in the high-risk emphysematous patient.

Article Title: Reference intervals for rotational thromboelastometry measurements using the ROTEM® delta device in dogs.
Article Snippet: Aims of the present study were to define reference intervals for viscoelastic analyses of canine haemostasis using the ROTEM® delta analyser, and as a secondary aspect to determine the precision (repeatability) of this method.. Blood samples from 125 clinically healthy dogs were included.. Measurements were performed with commercially available activating reagents (ex-tem, in-tem and kaolin solution) as well as without activation.

FIBTEM Assay:

Article Title: Viscoelastometry to Manage Bleeding in Liver Disease
Article Snippet: .. Examples of tests employed by two instruments, ROTEM and ClotPro, in the setting of liver disease are the EXTEM (ROTEM) and EX-test (ClotPro) that test the extrinsic pathway, INTEM (ROTEM) and IN-test (ClotPro) that test the intrinsic pathway, FIBTEM (ROTEM) and FIB-test (ClotPro) that assess fibrinogen contribution, and APTEM (ROTEM) and AP-test (ClotPro) that evaluate fibrinolysis. .. NATEM (ROTEM) and NA-test (ClotPro) have also been used by some investigators.

Article Title: Platelet-leucocyte aggregation is augmented in cirrhosis and further increased by platelet transfusion.
Article Snippet: The markers of platelet activation (sP-selectin and sCD40L), the proinflammatory cytokine monocyte chemoattractant protein-1 (MCP-1) and the endothelial activation markers (sICAM-1, sVCAM-1 and sPselectin) were quantified using cytometric bead array (BD, UK) from the previously stored plasmas. .. Thromboelastometry was performed on citrated whole blood using Rotem and the assay panel included INTEM, EXTEM, FIBTEM and APTEM. ..

Article Title: Effect of the colloids gelatin and HES 130/0.4 on blood coagulation in cardiac surgery patients: a randomized controlled trial.
Article Snippet: Objective: The choice of the prime solution for cardiopulmonary bypass can play an important role in limiting the effect on blood coagulation, but it is still unclear what the effect of colloids on blood coagulation is.. The aim of this study was to investigate the effect of synthetic colloids on blood loss and blood coagulation in patients after on-pump coronary artery bypass graft (CABG) procedures.. Methods: Sixty elective, on-pump CABG patients were randomly assigned to receive the prime solutions lactated Ringer’s solution combined with hydroxyethyl starch 130/0.4 (HES, 6% Volulyte, Fresenius Kabi Nederland BV, Zeist, the Netherlands) (HES group) or gelatin (Gelofusin®, B Braun Melsung AG, Melsungen, Germany) (Gelo group).



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Graphical representation of <t>ROTEM</t> assay (EXTEM, <t>INTEM,</t> FIBTEM). ROTEM = <t>Rotational</t> <t>thromboelastometry</t>
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CT <t>INTEM</t> (clotting time) and ROC analysis for mortality ( left graph ). Box and whisker plot with the 10th and 90th percentiles ( right graph ). Solid line in the box: median values of CT INTEM . The plus symbol in the box: mean values of CT INTEM . Blue line : optimal threshold for CT INTEM in prediction of 30-day mortality. Receiver operating characteristic curves (ROC) were constructed (C-statistic) to evaluate the predictive power of CT INTEM for 30-day mortality. AUC area-under-the-curve. The Youden Index was used to calculate optimal threshold for CT INTEM in prediction of 30-day mortality. Data were collected in real-time by the attending physician or nurse in parallel to the patient treatment. Each patient was considered only once. If more than one Rotem (rotational thromboelastometry) analysis was done in one patient, only the first Rotem analysis was considered
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CT <t>INTEM</t> (clotting time) and ROC analysis for mortality ( left graph ). Box and whisker plot with the 10th and 90th percentiles ( right graph ). Solid line in the box: median values of CT INTEM . The plus symbol in the box: mean values of CT INTEM . Blue line : optimal threshold for CT INTEM in prediction of 30-day mortality. Receiver operating characteristic curves (ROC) were constructed (C-statistic) to evaluate the predictive power of CT INTEM for 30-day mortality. AUC area-under-the-curve. The Youden Index was used to calculate optimal threshold for CT INTEM in prediction of 30-day mortality. Data were collected in real-time by the attending physician or nurse in parallel to the patient treatment. Each patient was considered only once. If more than one Rotem (rotational thromboelastometry) analysis was done in one patient, only the first Rotem analysis was considered
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CT <t>INTEM</t> (clotting time) and ROC analysis for mortality ( left graph ). Box and whisker plot with the 10th and 90th percentiles ( right graph ). Solid line in the box: median values of CT INTEM . The plus symbol in the box: mean values of CT INTEM . Blue line : optimal threshold for CT INTEM in prediction of 30-day mortality. Receiver operating characteristic curves (ROC) were constructed (C-statistic) to evaluate the predictive power of CT INTEM for 30-day mortality. AUC area-under-the-curve. The Youden Index was used to calculate optimal threshold for CT INTEM in prediction of 30-day mortality. Data were collected in real-time by the attending physician or nurse in parallel to the patient treatment. Each patient was considered only once. If more than one Rotem (rotational thromboelastometry) analysis was done in one patient, only the first Rotem analysis was considered
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CT <t>INTEM</t> (clotting time) and ROC analysis for mortality ( left graph ). Box and whisker plot with the 10th and 90th percentiles ( right graph ). Solid line in the box: median values of CT INTEM . The plus symbol in the box: mean values of CT INTEM . Blue line : optimal threshold for CT INTEM in prediction of 30-day mortality. Receiver operating characteristic curves (ROC) were constructed (C-statistic) to evaluate the predictive power of CT INTEM for 30-day mortality. AUC area-under-the-curve. The Youden Index was used to calculate optimal threshold for CT INTEM in prediction of 30-day mortality. Data were collected in real-time by the attending physician or nurse in parallel to the patient treatment. Each patient was considered only once. If more than one Rotem (rotational thromboelastometry) analysis was done in one patient, only the first Rotem analysis was considered
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CT <t>INTEM</t> (clotting time) and ROC analysis for mortality ( left graph ). Box and whisker plot with the 10th and 90th percentiles ( right graph ). Solid line in the box: median values of CT INTEM . The plus symbol in the box: mean values of CT INTEM . Blue line : optimal threshold for CT INTEM in prediction of 30-day mortality. Receiver operating characteristic curves (ROC) were constructed (C-statistic) to evaluate the predictive power of CT INTEM for 30-day mortality. AUC area-under-the-curve. The Youden Index was used to calculate optimal threshold for CT INTEM in prediction of 30-day mortality. Data were collected in real-time by the attending physician or nurse in parallel to the patient treatment. Each patient was considered only once. If more than one Rotem (rotational thromboelastometry) analysis was done in one patient, only the first Rotem analysis was considered
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Image Search Results


Graphical representation of ROTEM assay (EXTEM, INTEM, FIBTEM). ROTEM = Rotational thromboelastometry

Journal: Indian Journal of Anaesthesia

Article Title: Rotational thromboelastometry (ROTEM) based comparison of coagulation parameters in transurethral resection of the prostate surgery using saline versus glycine as an irrigant fluid – A prospective observational comparative study

doi: 10.4103/ija.ija_553_25

Figure Lengend Snippet: Graphical representation of ROTEM assay (EXTEM, INTEM, FIBTEM). ROTEM = Rotational thromboelastometry

Article Snippet: ROTEM – INTEM , Clotting time (CT, s) , 176.05 (52.97) , 152.58 (SD: 25.23) , 0.013 , — , —.

Techniques: FIBTEM Assay

CT INTEM (clotting time) and ROC analysis for mortality ( left graph ). Box and whisker plot with the 10th and 90th percentiles ( right graph ). Solid line in the box: median values of CT INTEM . The plus symbol in the box: mean values of CT INTEM . Blue line : optimal threshold for CT INTEM in prediction of 30-day mortality. Receiver operating characteristic curves (ROC) were constructed (C-statistic) to evaluate the predictive power of CT INTEM for 30-day mortality. AUC area-under-the-curve. The Youden Index was used to calculate optimal threshold for CT INTEM in prediction of 30-day mortality. Data were collected in real-time by the attending physician or nurse in parallel to the patient treatment. Each patient was considered only once. If more than one Rotem (rotational thromboelastometry) analysis was done in one patient, only the first Rotem analysis was considered

Journal: Die Anaesthesiologie

Article Title: A clotting time longer than 226 s in the INTEM channel of the thromboelastometer is an independent risk factor for mortality during bleeding

doi: 10.1007/s00101-025-01602-w

Figure Lengend Snippet: CT INTEM (clotting time) and ROC analysis for mortality ( left graph ). Box and whisker plot with the 10th and 90th percentiles ( right graph ). Solid line in the box: median values of CT INTEM . The plus symbol in the box: mean values of CT INTEM . Blue line : optimal threshold for CT INTEM in prediction of 30-day mortality. Receiver operating characteristic curves (ROC) were constructed (C-statistic) to evaluate the predictive power of CT INTEM for 30-day mortality. AUC area-under-the-curve. The Youden Index was used to calculate optimal threshold for CT INTEM in prediction of 30-day mortality. Data were collected in real-time by the attending physician or nurse in parallel to the patient treatment. Each patient was considered only once. If more than one Rotem (rotational thromboelastometry) analysis was done in one patient, only the first Rotem analysis was considered

Article Snippet: Die C‐Statistik zeigte, dass CT INTEM (C-Statistik = 0,62, optimaler Schwellenwert > 226 s) prädiktiv für die 30-Tage-Sterblichkeit war.

Techniques: Coagulation, Whisker Assay, Construct

All patients ( n = 2197) and subgroups analyses in patients with ( n = 823) or without ( n = 1374) cardiopulmonary bypass. Kaplan-Meier survival plots for terciles of clotting time (CT INTEM ), CT INTEM > 226 s versus CT INTEM ≤ 226s for 30 days follow-up. ROTEM rotational thromboelastometry, CPB cardiopulmonary bypass

Journal: Die Anaesthesiologie

Article Title: A clotting time longer than 226 s in the INTEM channel of the thromboelastometer is an independent risk factor for mortality during bleeding

doi: 10.1007/s00101-025-01602-w

Figure Lengend Snippet: All patients ( n = 2197) and subgroups analyses in patients with ( n = 823) or without ( n = 1374) cardiopulmonary bypass. Kaplan-Meier survival plots for terciles of clotting time (CT INTEM ), CT INTEM > 226 s versus CT INTEM ≤ 226s for 30 days follow-up. ROTEM rotational thromboelastometry, CPB cardiopulmonary bypass

Article Snippet: Die C‐Statistik zeigte, dass CT INTEM (C-Statistik = 0,62, optimaler Schwellenwert > 226 s) prädiktiv für die 30-Tage-Sterblichkeit war.

Techniques: Coagulation